Hydrogen sulphide, the gas responsible for the terrible smell of rotten eggs, has been found to play a role in the biochemical response that leads to an erection. The discovery may lead to a new medical therapy for Erectile Dysfunction.
In the
Proceedings of the National Academy of Sciences, Italian researchers showed that hydrogen sulphide is released into the erectile tissues prior to erections occurring. Current Erectile Dysfunction drugs, such as Viagra, Cialis and Levitra, target
nitric oxide, another mediator in erections.
In some rare cases, men do not respond to the current Erectile Dysfunction drugs which target the nitric oxide pathway. New medications directed at hydrogen sulphide would hold promise for these patients.
Prior to being released as an effective medication to treat ED, sildenafil (Viagra) was being investigated as a medication to treat and prevent heart disease.
Now a study published in a recent Journal of Clinical Investigation suggests that Viagra may have a protective effect on the heart muscle in cases of hypertension. Viagra may decrease dangerous hypertrophy in heart muscle which can ultimately lead to heart failure. The study used an animal model and further research will be needed to see if the same beneficial effect exists in humans.
Erectile dysfunction, to some degree, affects perhaps 50% of men between the ages of 40 and 70. The impact on quality of life as well as a man's sense of well being is truly staggering. With the introduction of sildenafil citrate (Viagra) in 1998, the approach and treatment of men with ED changed dramatically. It was no longer necessary to subject most men to extensive and costly diagnostic testing and often embarrassing face to face encounters in order to safely offer them treatment. But how do Viagra and the other ED drugs work exactly? They work their magic by inhibiting a specific enzyme called phosphodiesterase 5 (PDE5). OK, here's what happens: during sexual stimulation, nitric oxide (NO) is released into the tissues of the penis. NO then causes an increase in cyclic GMP which allow the erectile tissues of the penis to engorge with arterial blood, while the venous drainage of the blood slows down.The ED drugs block the breakdown of cGMP, which allows it to do its job more efficiently and powerfully. While that might be "too much information," it's good to know what medications really do. And besides, now you know more about the mechanism of action of the ED medications than most physicians!
KwikMed's customer service team receives numerous questions every week from our customers regarding generic Viagra the risks involved when purchasing medications online.
When buying Viagra online it is very important to understand the risks involved when dealing with unregulated online pharmacies. There has been a sharp rise in the number of counterfeit pharmaceutical products being sold online.
These fake products may look like the real thing but do not contain the proper substances and can be very dangerous.
It is also important to realize that there is no such thing as "generic" Viagra, Cialis, or Levitra. Although you frequently see these "generic" erectile dysfunction medicines being advertised online they are not legal and it's illegal to sell "generic" Viagra, Cialis, or Levitra in the United States. These impotence drugs are not FDA approved which means you cannot be sure that these products are effective or safe.
The
Pfizer website provides guidelines for buying Pfizer Viagra and notes that there are thousands of websites selling fake Viagra. It urges you to protect yourself and stay away from any sites selling "generic" Viagra, Viagra soft tabs, and quick-dissolving Viagra as these are all forms of fake Viagra.
Powered by Compendium Blogware